Covid e Vitamina D

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covid 19 e vitamina D
covid 19 e vitamina d

Covid e Vitamina D. Numerose e serie evidenze scientifiche sottolineano l’importanza della terapia con vitamina D per difenderci dal Covid 19. E’ fondamentale nella prevenzione ma anche estremamente importante nella cura delle persone sintomatiche da infezione virale SARS COV2. E’ stato infatti visto che il trattamento con alte dosi di vitamina D fa riprendere velocemente la salute dei pazienti, anche quelli in terapia intensiva. Abbassa, quindi, il rischio di aggravamento della malattia riducendone, quindi, la mortalità.

Vi riporto due, dei tanti articoli, scritti da professionisti di tutto il mondo. Metterò i Link per cui, chi avrà piacere di leggere l’intero articolo lo potrà fare. Sono in inglese perché gli articoli medici nelle riviste importanti del settore sono in inglese, proprio per far comunicare i medici di ogni nazione…. e allora mi viene una domanda: “ma perché, se molti sanno, pochi attuano questa facile prescrizione medica?”

J Infect Public Health. 2020 Oct;13(10):1373-1380.Role of vitamin D in preventing of COVID-19 infection, progression and severity. Nurshad Ali 

Abstract

The outbreak of COVID-19 has created a global public health crisis. Little is known about the protective factors of this infection. Therefore, preventive health measures that can reduce the risk of infection, progression and severity are desperately needed. This review discussed the possible roles of vitamin D in reducing the risk of COVID-19 and other acute respiratory tract infections and severity. Moreover, this study determined the correlation of vitamin D levels with COVID-19 cases and deaths in 20 European countries as of 20 May 2020.

A significant negative correlation (p=0.033) has been observed between mean vitamin D levels and COVID-19 cases per one million population in European countries. However, the correlation of vitamin D with COVID-19 deaths of these countries was not significant. Some retrospective studies demonstrated a correlation between vitamin D status and COVID-19 severity and mortality, while other studies did not find the correlation when confounding variables are adjusted. Several studies demonstrated the role of vitamin D in reducing the risk of acute viral respiratory tract infections and pneumonia. These include direct inhibition with viral replication or with anti-inflammatory or immunomodulatory ways.

Conclusion

In the meta-analysis, vitamin D supplementation has been shown as safe and effective against acute respiratory tract infections. Thus, people who are at higher risk of vitamin D deficiency during this global pandemic should consider taking vitamin D supplements to maintain the circulating 25(OH)D in the optimal levels (75-125nmol/L). In conclusion, there is not enough evidence on the association between vitamin D levels and COVID-19 severity and mortality. Therefore, randomized control trials and cohort studies are necessary to test this hypothesis.

Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths. Nutrients. 2020 Apr 2;12(4):988.William B Grant1Henry Lahore2Sharon L McDonnell3Carole A Baggerly3Christine B French3Jennifer L Aliano3Harjit P Bhattoa4

Abstract

The world is in the grip of the COVID-19 pandemic. Public health measures that can reduce the risk of infection and death in addition to quarantines are desperately needed. This article reviews the roles of vitamin D in reducing the risk of respiratory tract infections, knowledge about the epidemiology of influenza and COVID-19, and how vitamin D supplementation might be a useful measure to reduce risk. Through several mechanisms, vitamin D can reduce risk of infections. Those mechanisms include inducing cathelicidins and defensins that can lower viral replication rates and reducing concentrations of pro-inflammatory cytokines that produce the inflammation that injures the lining of the lungs, leading to pneumonia, as well as increasing concentrations of anti-inflammatory cytokines.

Several observational studies and clinical trials reported that vitamin D supplementation reduced the risk of influenza, whereas others did not. Evidence supporting the role of vitamin D in reducing risk of COVID-19 includes that the outbreak occurred in winter, a time when 25-hydroxyvitamin D (25(OH)D) concentrations are lowest; that the number of cases in the Southern Hemisphere near the end of summer are low; that vitamin D deficiency has been found to contribute to acute respiratory distress syndrome; and that case-fatality rates increase with age and with chronic disease comorbidity, both of which are associated with lower 25(OH)D concentration.

Conclusion

To reduce the risk of infection, it is recommended that people at risk of influenza and/or COVID-19 consider taking 10,000 IU/d of vitamin D3 for a few weeks to rapidly raise 25(OH)D concentrations, followed by 5000 IU/d. The goal should be to raise 25(OH)D concentrations above 40-60 ng/mL (100-150 nmol/L). For treatment of people who become infected with COVID-19, higher vitamin D3 doses might be useful. Randomized controlled trials and large population studies should be conducted to evaluate these recommendations.

Covid 19 e Vitamina D
Covid 19 e Vitamina D

Covid 19 e Vitamina D… Riflettiamo.

“Quindi, capite quanto deve essere il dosaggio della vitamina d nel sangue affinché possiate proteggervi dal COV 2?”

I range di riferimento normali, che trovate sui referti di laboratorio sono: 30-100. Per cui mi domando perché, visto l’importanza di questa vitamina, ci sia tutta questa difficoltà nel prescriverla. Non possiamo accontentarci di avere 20 o 30 di livelli di vitamina D nel sangue!

E poi, ricordiamoci l’importanza di questa vitamina nel combattere il cancro! E’ un guerriero prezioso che ci difende da trasformazioni maligne. Il cancro è un tessuto che ama l’acidosi, sguazza e prolifera beatamente nell’acidità… I nostri tessuti si stanno acidificando sempre di più. E’ da marzo 2020 che respiriamo la nostra stessa anidride carbonica … Ricordate parole come acido lattico, anidride carbonica, acidosi tessutale? … Beh, ad ognuno lascio le proprie conclusioni.

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