Covid and Vitamin D

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Covid 19 e Vitamin D
Covid 19 and Vitamin D

Covid and Vitamin D. Numerous and serious scientific evidence underlines the importance of vitamin D therapy to defend ourselves against Covid 19. It is fundamental in prevention but also extremely important in the treatment of people symptomatic of SARS COV2 viral infection. In fact, it has been seen that treatment with high doses of vitamin D quickly regains the health of patients, even those in intensive care. Therefore, it lowers the risk of aggravation of the disease, thus reducing mortality.

Here are two of the many articles written by professionals from all over the world. I will put the Links so whoever likes to read the entire article can do it.

J Infect Public Health. 2020 Oct;13(10):1373-1380.Role of vitamin D in preventing of COVID-19 infection, progression and severity. Nurshad Ali

Abstract

The outbreak of COVID-19 has created a global public health crisis. Little is known about the protective factors of this infection. Therefore, preventive health measures that can reduce the risk of infection, progression and severity are desperately needed. This review discussed the possible roles of vitamin D in reducing the risk of COVID-19 and other acute respiratory tract infections and severity. Moreover, this study determined the correlation of vitamin D levels with COVID-19 cases and deaths in 20 European countries as of 20 May 2020. 

A significant negative correlation (p=0.033) has been observed between mean vitamin D levels and COVID-19 cases per one million population in European countries. However, the correlation of vitamin D with COVID-19 deaths of these countries was not significant. Some retrospective studies demonstrated a correlation between vitamin D status and COVID-19 severity and mortality, while other studies did not find the correlation when confounding variables are adjusted. Several studies demonstrated the role of vitamin D in reducing the risk of acute viral respiratory tract infections and pneumonia. These include direct inhibition with viral replication or with anti-inflammatory or immunomodulatory ways. 

Conclusion

In the meta-analysis, vitamin D supplementation has been shown as safe and effective against acute respiratory tract infections. Thus, people who are at higher risk of vitamin D deficiency during this global pandemic should consider taking vitamin D supplements to maintain the circulating 25(OH)D in the optimal levels (75-125nmol/L). In conclusion, there is not enough evidence on the association between vitamin D levels and COVID-19 severity and mortality. Therefore, randomized control trials and cohort studies are necessary to test this hypothesis.

Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths. Nutrients. 2020 Apr 2;12(4):988.William B Grant1Henry Lahore2Sharon L McDonnell3Carole A Baggerly3Christine B French3Jennifer L Aliano3Harjit P Bhattoa4

Abstract

The world is in the grip of the COVID-19 pandemic. Public health measures that can reduce the risk of infection and death in addition to quarantines are desperately needed. This article reviews the roles of vitamin D in reducing the risk of respiratory tract infections, knowledge about the epidemiology of influenza and COVID-19, and how vitamin D supplementation might be a useful measure to reduce risk. Through several mechanisms, vitamin D can reduce risk of infections. Those mechanisms include inducing cathelicidins and defensins that can lower viral replication rates and reducing concentrations of pro-inflammatory cytokines that produce the inflammation that injures the lining of the lungs, leading to pneumonia, as well as increasing concentrations of anti-inflammatory cytokines.

Several observational studies and clinical trials reported that vitamin D supplementation reduced the risk of influenza, whereas others did not. Evidence supporting the role of vitamin D in reducing risk of COVID-19 includes that the outbreak occurred in winter, a time when 25-hydroxyvitamin D (25(OH)D) concentrations are lowest; that the number of cases in the Southern Hemisphere near the end of summer are low; that vitamin D deficiency has been found to contribute to acute respiratory distress syndrome; and that case-fatality rates increase with age and with chronic disease comorbidity, both of which are associated with lower 25(OH)D concentration.

Conclusion

To reduce the risk of infection, it is recommended that people at risk of influenza and/or COVID-19 consider taking 10,000 IU/d of vitamin D3 for a few weeks to rapidly raise 25(OH)D concentrations, followed by 5000 IU/d. The goal should be to raise 25(OH)D concentrations above 40-60 ng/mL (100-150 nmol/L). For treatment of people who become infected with COVID-19, higher vitamin D3 doses might be useful. Randomized controlled trials and large population studies should be conducted to evaluate these recommendations.

Covid and Vitamin D
Covid and Vitamin D

Covid 19 and Vitamin D… Let’s reflect.

“So, do you understand what the dosage of life d must be in the blood in order for you to protect yourself from VOC 2?”

The normal reference ranges found on laboratory reports are: 30-100. So I wonder why, given the importance of this vitamin, there is all this difficulty in prescribing it. We cannot be satisfied with having 20 or 30 levels of vitamin D in the blood!

And then, let’s remember the importance of this vitamin in fighting cancer! He is a precious warrior who defends us from evil transformations. Cancer is a tissue that loves acidosis, wallows and proliferates blissfully in acidity … Our tissues are becoming more acidified. We have been breathing our own carbon dioxide since March 2020 … Do you remember words like lactic acid, carbon dioxide, tissue acidosis? … Well, I leave everyone their own conclusions.

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